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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2364506Generated: November 1, 2026

4-Aminotetrahydropyran → HCID 69482700, compound

https://huagongshe.com/reaction/2364506

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-AminotetrahydropyranHCID 419223—
ReactantEthyl 7-[(4-fluorophenyl)methyl]-4-hydroxy-2-oxo-1-[2-(2-oxo-1-piperidinyl)ethyl]-1,2-dihydro-1,5-naphthyridine-3-carboxylateHCID 69482570—
ProductHCID 69482700HCID 69482700—

Reaction Steps

This compound was prepared from ethyl 7-[(4-fluorophenyl)methyl]-4-hydroxy-2-oxo-1-[2-(2-oxo-1-piperidinyl)ethyl]-1,2-dihydro-1,5-naphthyridine-3-carboxylate and tetrahydro-2H-pyran-4-amine using methods similar to Example 563 to provide a white solid: ES+ MS: 523 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08691991B2
Source datasetuspto-grants-2014_04
ORD IDord-5724c4e9571f483aa0c552018549a11d
Source noteuspto-grants-2014_04