9-Borabicyclo(3.3.1)nonane → 4-(3-(9-Borabicyclo[3.3.1]nonan-9-yl)propyl)morpholine

Participants

Reaction Steps

To a solution of 4-allylmorpholine (2.54 g, 20 mmol) in THF (40 mL) was added 9-BBN (2.44 g, 10 mmol). The reaction mixture was refluxed until the reaction was complete. After cooling to room temperature, the mixture was concentrated under reduced pressure to give the crude 4-(3-(9-borabicyclo[3.3.1]nonan-9-yl)propyl)morpholine that was used directly without further purification. LCMS ESI (+) m/z 250 (M+1) detected.

Provenance & Evidence