HCID 68106974, compound → HCID 68107212, compound

Participants

Reaction Steps

Methyl 3-(2-methylallyloxy)-4-nitro-benzoate 4a (4.52 g, 18 mmol) was heated to 190° C. and stirred for 3 hours. The reaction mixture was cooled down to room temperature followed by the addition of 50 mL of dichloromethane. The reaction solution was concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography to obtain the title compound methyl 3-hydroxy-2-(2-methylallyl)-4-nitro-benzoate 4b (2.60 g, yield: 57.7%) as a yellow oil.

Provenance & Evidence