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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2364804Generated: October 30, 2026

Tetrahydrofuran → HCID 178451914, compound

https://huagongshe.com/reaction/2364804

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantHCID 178418361HCID 178418361—
ReactantHCID 178451916HCID 178451916—
CatalystAdams' catalystHCID 345198—
SolventEthanolHCID 702—
ProductHCID 178451914HCID 178451914100%

Reaction Steps

The product from example 40C (1.37 g, 2.153 mmol), in ethanol (10 mL) and THF (10 mL) then added platinum(IV) oxide (196 mg, 0.862 mmol) and a hydrogen balloon and stirred the solution at room temperature for 48 h. The reaction was then treated according to the procedure in Example 39G to provide the title compound (1.3 g, 100%) as a mixture of stereoisomers.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08691938B2
Source datasetuspto-grants-2014_04
ORD IDord-ae9db1d0d4ca4ebe86c14bd395ed0995
Source noteuspto-grants-2014_04