HRID236482

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6287

L-Valine

C5H11NO2

结构：CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCC)C(=O)O

HCID13371862

2-(Hexadecanoyloxy)hexadecanoic acid

C32H62O4

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCC)C(=O)N[C@H](C(=O)O)C(C)C

HCID54524559

N-[2-(Hexadecanoyloxy)hexadecanoyl]-L-valine

C37H71NO5

收率 82.1%

PROCEDURE

实验过程

Starting from 2-hexadecanoyloxyhexadecanoic acid (2.55 g) prepared by the method described in Preparation A-3 and L-valine (2.34 g), N-(2-hexadecanoyloxyhexadecanoyl)-L-valine (2.5 g) was obtained as crystals according to a similar manner to that of Preparation B-1.

WORKUP

后处理

customprepared by the method

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-7e5b788501df43d6ba550fa0f213c8a2
来源数据集: uspto-grants-1987_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04643990
来源说明: uspto-grants-1987_02

反应 SMILES

[C:1]([O:18][CH:19]([CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])[C:20]([OH:22])=O)(=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[NH2:37][C@H:38]([C:42]([OH:44])=[O:43])[CH:39]([CH3:41])[CH3:40]>>[C:1]([O:18][CH:19]([CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])[C:20]([NH:37][C@H:38]([C:42]([OH:44])=[O:43])[CH:39]([CH3:41])[CH3:40])=[O:22])(=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]