Water → 6-(Morpholino)pyridin-3-amine

Participants

Reaction Steps

To a solution of the product from Example 154A (12.5, 59.5 mmol) in THF (150 mL) was added to Ra—Ni 2800, water slurry (12.5 g, 212 mmol) in a 500 mL SS pressure bottle. The mixture was pressurized (H2, 30 psi) and stirred for 2 hours at room temperature. The mixture was filtered and then concentrated under reduced pressure to provide the title compound.

Provenance & Evidence