HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Glutamic acid dibenzyl ester → dibenzyl N-[N-(2-hexadecanoyloxyhexadecanoyl)-L-valyl]-L-glutamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Glutamic acid dibenzyl ester | HCID 3037947 | — |
| Reactant | N-[2-(Hexadecanoyloxy)hexadecanoyl]-L-valine | HCID 54524559 | — |
| Product | dibenzyl N-[N-(2-hexadecanoyloxyhexadecanoyl)-L-valyl]-L-glutamate | HCID 54284467 | 90.4% |
Reaction Steps
Starting from N-(2-hexadecanoyloxyhexadecanoyl)-L-valine (2.4 g) prepared by the method of Preparation B-2 and dibenzyl L-glutamate (1.26 g), dibenzyl N-[N-(2-hexadecanoyloxyhexadecanoyl)-L-valyl]-L-glutamate (3.2 g) was obtained as crystals according to a similar manner to that of Example 2. M.p. 65° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04643990 |
| Source dataset | uspto-grants-1987_02 |
| ORD ID | ord-de28c504e8254c2ca7ddeea630eaa863 |
| Source note | uspto-grants-1987_02 |