HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Glutamic acid dibenzyl ester → dibenzyl N-[N-[N-(3-hexadecanoyloxyoctadecanoyl)-beta-alanyl]-L-threonyl]-L-glutamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Glutamic acid dibenzyl ester | HCID 3037947 | — |
| Reactant | N-[N-(3-hexadecanoyloxyoctadecanoyl)-beta-alanyl]-L-threonine | HCID 54384255 | — |
| Product | dibenzyl N-[N-[N-(3-hexadecanoyloxyoctadecanoyl)-beta-alanyl]-L-threonyl]-L-glutamate | HCID 86741312 | 38.7% |
Reaction Steps
Starting from N-[N-(3-hexadecanoyloxyoctadecanoyl)-β-alanyl]-L-threonine (450 mg) prepared by the method of Preparation B-4 and dibenzyl L-glutamate (210 mg), dibenzyl N-[N-[N-(3-hexadecanoyloxyoctadecanoyl)-β-alanyl]-L-threonyl]-L-glutamate (250 mg) was obtained as crystals according to a similar manner to that of Example 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04643990 |
| Source dataset | uspto-grants-1987_02 |
| ORD ID | ord-2925fb08182a40fab31ec394d5cdcec6 |
| Source note | uspto-grants-1987_02 |