HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Glutamic Acid → N-[Nalpha-(3-hexadecanoyloxyoctadecanoyl)-Nepsilon-benzyloxycarbonyl-L-lysyl]-L-glutamic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Glutamic Acid | HCID 33032 | — |
| Reactant | Nalpha-(3-hexadecanoyloxyoctadecanoyl)-Nepsilon-benzyloxycarbonyl-L-lysine | HCID 70533277 | — |
| Product | N-[Nalpha-(3-hexadecanoyloxyoctadecanoyl)-Nepsilon-benzyloxycarbonyl-L-lysyl]-L-glutamic acid | HCID 86741313 | 68.9% |
Reaction Steps
Starting from N-hydroxysuccinimide ester of Nα -(3-hexadecanoyloxyoctadecanoyl)-Nε -benzyloxycarbonyl-L-lysine (3 g) prepared above and L-glutamic acid (1.18 g), N-[Nα -(3-hexadecanoyloxyoctadecanoyl)-Nε -benzyloxycarbonyl-L-lysyl]-L-glutamic acid (2.4 g) was obtained as crystals according to a similar manner to that of Example 16(2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04643990 |
| Source dataset | uspto-grants-1987_02 |
| ORD ID | ord-52cab8564f564df6bf0dd4b4ffcd6ac2 |
| Source note | uspto-grants-1987_02 |