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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2364982Generated: October 30, 2026

5-Bromo-2-oxindole → HCID 86637671, compound

https://huagongshe.com/reaction/2364982

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-oxindoleHCID 611193—
Reactant5-(2-diethylaminoethyl)-3-methyl-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehydeHCID 25023015—
ProductHCID 66607579HCID 66607579—
ProductHCID 86637671HCID 8663767198.7%

Reaction Steps

The title compound was prepared under the same conditions as described in Example 1 with 5-(2-diethylamino-ethyl)-3-methyl-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehyde and 5-bromo-1,3-dihydro-indole-2-one (commercially available from Aldrich) as starting materials to give 2-(5-bromo-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-5-2-diethylamino-ethyl)-3-methyl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one (56 mg, 98.7%) as a brown solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08697692B2
Source datasetuspto-grants-2014_04
ORD IDord-85cf8435036d48ff9dd1b8e27b0441c8
Source noteuspto-grants-2014_04