dibenzyl N-(N-butanoyl-L-valyl)-L-glutamate → N-(N-butanoyl-L-valyl)-L-glutamic acid

Participants

Reaction Steps

A mixture of dibenzyl N-(N-butanoyl-L-valyl)-L-glutamate (613 mg) and palladium black (50 mg) in methanol (50 ml) was subjected to catalytic hydrogenation under atmospheric pressure. After the reaction mixture was filtered, the filtrate was concentrated under reduced pressure to give a residue which was recrystallized from petroleum ether to afford N-(N-butanoyl-L-valyl)-L-glutamic acid as crystals (343 mg).

Provenance & Evidence