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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2365013Generated: October 30, 2026

7-Amino-5-fluoroindolin-2-one → HCID 66608553, compound

https://huagongshe.com/reaction/2365013

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Amino-5-fluoroindolin-2-oneHCID 59250054—
Reactant3-methyl-5-(2-morpholin-4-yl-ethyl)-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehydeHCID 86637676—
ProductHCID 66608553HCID 6660855343.8%

Reaction Steps

The title compound was prepared under the same conditions as described in Example 15 with 3-methyl-5-(2-morpholin-4-yl-ethyl)-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehyde and 5-fluoro-7-amino-1,3-dihydro-indol-2-one as starting materials to give 2-(7-amino-5-fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-3-methyl-5-(2-morpholin-4-yl-ethyl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one (35 mg, 43.8%) as a red solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08697692B2
Source datasetuspto-grants-2014_04
ORD IDord-d866fa80a17d47eab78e9b234b15b107
Source noteuspto-grants-2014_04