HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Threonine → N-[Nalpha-(3-hexadecanoyloxyoctadecanoyl)-Nepsilon-benzyloxycarbonyl-L-lysyl]-L-threonine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Threonine | HCID 6288 | — |
| Reactant | Nalpha-(3-hexadecanoyloxyoctadecanoyl)-Nepsilon-benzyloxycarbonyl-L-lysine | HCID 70533277 | — |
| Product | N-[Nalpha-(3-hexadecanoyloxyoctadecanoyl)-Nepsilon-benzyloxycarbonyl-L-lysyl]-L-threonine | HCID 86741316 | 79.5% |
Reaction Steps
Starting from Nα -(3-hexadecanoyloxyoctadecanoyl)-Nε -benzyloxycarbonyl-L-lysine (2.68 g) prepared by the method of Example 20 (1), and L-threonine (0.95 g), N-[Nα -(3-hexadecanoyloxyoctadecanoyl)-Nε -benzyloxycarbonyl-L-lysyl]-L-threonine (2.4 g) was obtained as crystals according to a similar manner to that of Example 32.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04643990 |
| Source dataset | uspto-grants-1987_02 |
| ORD ID | ord-5c5beb7c7dd342da8c0e8d57a8870e20 |
| Source note | uspto-grants-1987_02 |