Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2365089Generated: October 31, 2026

4-Methyl-1,3-dihydro-2H-indol-2-one → HCID 66607998, compound

https://huagongshe.com/reaction/2365089

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methyl-1,3-dihydro-2H-indol-2-oneHCID 12579382—
Reactant3-methyl-4-oxo-5-(2-piperidin-1-yl-ethyl)-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehydeHCID 86637677—
ProductHCID 66607998HCID 6660799875.9%

Reaction Steps

The title compound was prepared under the same conditions as described in Example 25 with 3-methyl-4-oxo-5-(2-piperidin-1-yl-ethyl)-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehyde and 4-methyl-1,3-dihydro-indol-2-one (prepared according to U.S. Pat. No. 6,114,371) as starting materials to give 3-methyl-2-(4-methyl-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-5-(2-piperidin-1-yl-ethyl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one (41 mg, 75.9%) as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08697692B2
Source datasetuspto-grants-2014_04
ORD IDord-a129331e2a5c4c6e948d17dfb84a714f
Source noteuspto-grants-2014_04