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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2365091Generated: October 30, 2026

7-Bromo-5-fluoroindolin-2-one → HCID 66607257, compound

https://huagongshe.com/reaction/2365091

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Bromo-5-fluoroindolin-2-oneHCID 53418888—
Reactant3-methyl-4-oxo-5-(2-piperidin-1-yl-ethyl)-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehydeHCID 86637677—
ProductHCID 66607257HCID 6660725787%

Reaction Steps

The title compound was prepared under the same conditions as described in Example 25 with 3-methyl-4-oxo-5-(2-piperidin-1-yl-ethyl)-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehyde and 5-fluoro-7-bromo-1,3-dihydro-indol-2-one as starting materials to give 2-(7-bromo-5-fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-3-methyl-5-(2-piperidin-1-yl-ethyl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one (57 mg, 87.0%) as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08697692B2
Source datasetuspto-grants-2014_04
ORD IDord-5d190edaa66e4988a5bb389fda371b2c
Source noteuspto-grants-2014_04