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HRID236512

反应详情

EQUATION

反应方程式

HRID 236512 的结构方程式

REACTANTS

反应物

2
反应SMILES：CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)N[C@H](C(=O)N[C@@H](CCC(=O)OCc1ccccc1)C(=O)OCc1ccccc1)[C@@H](C)O
HCID53724108

未命名化合物

反应SMILES：[H][H]
HCID178418361

未命名化合物

PRODUCTS

产物

1
反应SMILES：CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)[C@@H](C)O
HCID53775222

未命名化合物

收率 91.3%

AUXILIARIES

试剂、催化剂与溶剂

1
反应SMILES：[Pd]
催化剂HCID23938

Palladium

Pd

PROCEDURE

实验过程

Dibenzyl N-[N-(3-hexadecanoyloxyoctadecanoyl)-L-threonyl]-L-glutamate (48 g) in demethylformamide (500 ml) was hydrogenated over palladium black (1 g) at room temperature at 1 atmospheric pressure. After the theoritical amount of hydrogen was adsorbed, dimethylformamide was removed under reduced pressure. The residual crude crystal was recrystallized from ethanol to give N-[N-(3-hexadecanoyloxyoctadecanoyl)-L-threonyl]-L-glutamic acid (35.5 g).

WORKUP

后处理

  1. customdimethylformamide was removed under reduced pressure
  2. customThe residual crude crystal was recrystallized from ethanol