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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2365121Generated: October 31, 2026

5-fluoro-1,3-dihydro-2H-indol-2-one → HCID 66607491, compound

https://huagongshe.com/reaction/2365121

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-fluoro-1,3-dihydro-2H-indol-2-oneHCID 3731012—
ReactantHCID 86637688HCID 86637688—
ProductHCID 66607491HCID 6660749137.98%

Reaction Steps

The title compound was prepared under the same conditions as described in Example 1 with 5-(4-hydroxy-1-methyl-piperidin-4-ylmethyl)-3-methyl-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehyde and 5-fluoro-1,3-dihydro-indol-2-one as starting materials to give 2-(5-fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-5-(4-hydroxy-1-methyl-piperidin-4-ylmethyl)-3-methyl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one (16 mg, 37.98%) as an orange solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08697692B2
Source datasetuspto-grants-2014_04
ORD IDord-00d842a2ade64885bc56422423c8dd00
Source noteuspto-grants-2014_04