Malic Acid → HCID 66607315, compound

Participants

Reaction Steps

The title compound was prepared under the same conditions described in Example 132 with 2-(5-fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-3-methyl-5-(2-morpholin-4-yl-ethyl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one and 2-hydroxyl-succinic acid as starting materials to give 2-(5-fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-3-methyl-5-(2-morpholin-4-yl-ethyl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one malate (20 g, 95%) as a yellow solid.

Provenance & Evidence