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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2365254Generated: October 29, 2026

(1S,2S)-2-aminocyclohexanol → HCID 56643780, compound

https://huagongshe.com/reaction/2365254

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1S,2S)-2-aminocyclohexanolHCID 7057408—
ReactantHCID 13752889HCID 13752889—
ReactantHCID 68622221HCID 68622221—
ProductHCID 56643780HCID 56643780—

Reaction Steps

5-[(6-Methoxypyridin-3-yl)methyl]-1,2-dihydro-3H-benzo[e]isoindol-3-one was prepared employing the procedures described for the construction of 2-[(1S,2S)-2-hydroxycyclohexyl]-5-{[6-(methylthio)pyridine-3-yl]methyl}-1,2-dihydro-3H-benzo[e]isoindol-3-one in Example 10, substituting ammonium hydroxide for (1S,2S)-2-aminocyclohexanol, and substituting 5-(chloromethyl)-2-methoxypyridine for 5-(chloromethyl)-2-(methylthio)pyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08697690B2
Source datasetuspto-grants-2014_04
ORD IDord-a884ee47dcc84baea5bdc282e29da433
Source noteuspto-grants-2014_04