4-(4-Chlorophenethyl)piperazin-2-one → tert-Butyl 7-(4-(4-chlorophenethyl)-2-oxopiperazin-1-yl)-3,5-dimethyl-3,4-dihydro-1H-pyrido[4,3-b]indole-2(5H)-carboxylate

Beteiligte Stoffe

Reaktionsschritte

tert-Butyl 7-bromo-3,5-dimethyl-3,4-dihydro-1H-pyrido[4,3-b]indole-2(5H)-carboxylate (enantiomer A) (1.00 g, 2.64 mmol) and 4-(4-chlorophenethyl)piperazin-2-one (0.754 g, 3.16 mmol) were reacted following the procedure for Example 2 (step f) to provide the title compound (482 mg, 34%) as a foam: ESI MS m/z 538 [M+H]+.

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