HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methoxy-N-methyl-1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide → 2-phenyl-1-(1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methoxy-N-methyl-1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide | HCID 86707831 | — |
| Reactant | HCID 178418336 | HCID 178418336 | — |
| Product | 2-phenyl-1-(1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-ethanone | HCID 86707832 | 92% |
Reaction Steps
This compound was prepared by the reaction of benzylmagnesium chloride (2.0 M solution in THF) with N-methoxy-N-methyl-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide as described in General Method 1. The desired compound was obtained in 92% yield as a light yellow viscous oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08697697B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-80dc15e6c9b34509a8d981cdfb7c8680 |
| Source note | uspto-grants-2014_04 |