HCID 67086980, compound → HCID 67086723, compound

HRID 2365539Notes

Reaction equation

HRID 2365539 reaction equation
[NH2:1][C@@H:2]([CH2:18][NH2:19])[CH2:3][CH2:4][CH2:5][C:6]1[CH:17]=[CH:16][C:9]([O:10][CH2:11][C@H:12]([OH:15])[CH2:13][OH:14])=[CH:8][CH:7]=1.OC1C=CC(CCC[C@@H](NC(=O)[O-])CNC(=O)OC(C)(C)C)=CC=1.OC1C=CC(CCC[C@H](NC(=O)[O-])CNC(=O)OC(C)(C)C)=CC=1>>[NH2:1][C@H:2]([CH2:18][NH2:19])[CH2:3][CH2:4][CH2:5][C:6]1[CH:17]=[CH:16][C:9]([O:10][CH2:11][C@H:12]([OH:15])[CH2:13][OH:14])=[CH:8][CH:7]=1

Participants

4

Reactant 3

HCID 67086980HCID 67086980, compoundHCID 86652887HCID 86652887, compoundHCID 86652888HCID 86652888, compound2×

Product 1

HCID 67086723HCID 67086723, compound

Procedure

This compound is prepared analogously to Intermediate O replacing (R)-tert-butyl 5-(4-hydroxyphenyl)pentane-1,2-diyldicarbamate (Intermediate M with (S)-tert-butyl 5-(4-hydroxyphenyl)pentane-1,2-diyldicarbamate (Intermediate N); [M+H}+ 269

Sources & evidence

ORD record
ord-79d6f80086c94cd09b9b463737f29643
Source dataset
uspto-grants-2014_04
Patent number
US08697687B2

Reaction notes

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