Sodium Hydroxide → HCID 13565003, compound

Participants

Reaction Steps

14.5 g (26.22 mmol) of β-phthalimido-ethyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-benzoyloxyphenyl)-pyridine-5-carboxylate are suspended in 260 ml of ethanol, and 7 ml (140 mmol) of hydrazine hydrate in 20 ml of ethanol are added dropwise, while boiling. The mixture is boiled for 2 hours, cooled and filtered with suction. The resulting solid product is stirred with 200 mmol of 0.5 N sodium hydroxide solution for 30 minutes, filtered off with suction, washed with water and ethanol and dried. 9.5 g of crystals which are red-orange in color and have a melting point of 216° C. are obtained.

Provenance & Evidence