HCID 42604613, compound → HCID 24854975, compound

Participants

Reaction Steps

5-(3-{3-bromo-5-methylsulfanyl-2-[2-(4-methyl-thiazol-5-yl)-ethoxy]-benzylamino}-propylamino)-4H-thieno[3,2-b]pyridine-7-one was prepared by reductive amination of the aldehyde prepared in Example 4 with amine XVIII following method C, Scheme 1. 1H NMR (400 MHz, CD3OD) δ 8.75 (1H, s), 7.70 (1H, d), 7.41 (1H, s), 7.29 (1H, s), 6.98 (1H, d), 5.59 (1H, s), 4.13 (2H, t), 3.72 (2H, s), 3.33 (4H, m), 2.65 (2H, t), 2.46 (3H, s), 2.40 (3H, s), 1.73 (2H, d).

Provenance & Evidence