HCID 67345140, compound → HCID 24854976, compound

HRID 2365785Notes

Reaction equation

HRID 2365785 reaction equation
[Br:1][C:2]1[C:3]([O:12][CH2:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[C:4]([CH:7]=[C:8]([S:10][CH3:11])[CH:9]=1)[CH:5]=O.Cl.[NH2:22][CH2:23][CH2:24][CH2:25][NH:26][C:27]1[NH:32][C:31]2[CH:33]=[CH:34][S:35][C:30]=2[C:29](=[O:36])[CH:28]=1>>[Br:1][C:2]1[C:3]([O:12][CH2:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[C:4]([CH:7]=[C:8]([S:10][CH3:11])[CH:9]=1)[CH2:5][NH:22][CH2:23][CH2:24][CH2:25][NH:26][C:27]1[NH:32][C:31]2[CH:33]=[CH:34][S:35][C:30]=2[C:29](=[O:36])[CH:28]=1

Participants

3

Reactant 2

HCID 67345140HCID 67345140, compoundHCID 86623232HCID 86623232, compound

Product 1

HCID 24854976HCID 24854976, compound

Procedure

5-[3-(3-bromo-5-methylsulfanyl-2-phenethyloxy-benzylamino)-propylamino]-4H-thieno[3,2-b]pyridine-7-one was prepared by reductive amination of the aldehyde prepared in Example 3 with amine XVIII following method C.

Sources & evidence

ORD record
ord-d405be12a5e047908cf3715c1a4b508c
Source dataset
uspto-grants-2014_04
Patent number
US08697720B2

Reaction notes

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