2,6-Dichlorobenzoyl chloride → HCID 86668987, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 2,6-dichlorobenzoyl chloride (62 mg, 0.30 mmol) in DCM (4 mL) was slowly added to a cooled (0° C.) solution of 4-aminopyridin-3-yl diisopropylcarbamodithioate (100 mg, 0.37 mmol) in DCM (15 mL). The solution was stirred at 20° C. for 30 minutes. The mixture was concentrated under reduced pressure and the residue was purified by silica gel column chromatography, eluting with EtOAc/petroleum ether (1:4) to give the desired product as a yellow solid (20 mg, 15% yield). LCMS (ESI) m/z: 442.1 [M+H+].

Provenance & Evidence