5-Nitrofurfural → HCID 11965415, compound

HRID 2366375Notes

Reaction equation

HRID 2366375 reaction equation
[N+:1]([C:4]1[O:8][C:7]([CH:9]=O)=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH3:11][O:12][C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][C:21]=1[O:22][CH3:23])[CH2:16][C:17]#[N:18]>>[CH3:11][O:12][C:13]1[CH:14]=[C:15](/[C:16](=[CH:9]/[C:7]2[O:8][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=2)/[C:17]#[N:18])[CH:19]=[CH:20][C:21]=1[O:22][CH3:23]

Participants

3

Reactant 2

HCID 127745-NitrofurfuralHCID 667273,4-Dimethoxybenzeneacetonitrile

Product 1

HCID 11965415HCID 11965415, compoundYield 2.9%

Procedure

5-Nitro-2-furaldehyde (1.41 g) was condensed with 3,4-dimethoxybenzyl cyanide (1.77 g) through Method A (production step 2), to thereby yield the target product (yield: 88 mg, 2.9%).

Sources & evidence

ORD record
ord-b12d4c65844246149d14a6e49e7c08fd
Source dataset
uspto-grants-2014_04
Patent number
US08697742B2

Reaction notes

Loading…