Piperidine → HCID 11965417, compound

Participants

Reaction Steps

Through the procedure as employed in Production step 1, an amine moiety derived from piperidine (1.28 g) was introduced into 5-bromo-2-furaldehyde (875 mg), to thereby yield 5-piperidin-1-yl-furan-2-carbaldehyde (yield: 650 mg, 73%). The produced 5-piperidin-1-yl-furan-2-carbaldehyde (179 mg) was condensed with 3,4-dimethoxybenzyl cyanide (177 mg) through Method A (production step 2), to thereby yield the target product (yield: 100 mg, 30%).

Provenance & Evidence