3,4-Dimethoxybenzeneacetonitrile → HCID 11965501, compound

HRID 2366390Notes

Reaction equation

HRID 2366390 reaction equation
[CH3:1][O:2][C:3]1[N:8]=[CH:7][C:6]([CH:9]=O)=[CH:5][CH:4]=1.[CH3:11][O:12][C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][C:21]=1[O:22][CH3:23])[CH2:16][C:17]#[N:18]>>[CH3:11][O:12][C:13]1[CH:14]=[C:15](/[C:16](=[CH:9]/[C:6]2[CH:7]=[N:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)/[C:17]#[N:18])[CH:19]=[CH:20][C:21]=1[O:22][CH3:23]

Participants

3

Reactant 2

HCID 667273,4-DimethoxybenzeneacetonitrileHCID 33645766-Methoxypyridine-3-carbaldehyde

Product 1

HCID 11965501HCID 11965501, compoundYield 96%

Procedure

6-Methoxy-3-pyridinecarboxaldehyde (411 mg) was condensed with 3,4-dimethoxybenzyl cyanide (532 mg) through Method A (production step 2), to thereby yield the target product (yield: 850 mg, 96%).

Sources & evidence

ORD record
ord-d26e66e2c1554f3090007d74030f734c
Source dataset
uspto-grants-2014_04
Patent number
US08697742B2

Reaction notes

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