Veratraldehyde → HCID 67228529, compound

HRID 2366406Notes

Reaction equation

HRID 2366406 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]([CH2:6][C:7]#[N:8])=[CH:2]1.[CH3:9][O:10][C:11]1[CH:12]=[C:13]([CH:16]=[CH:17][C:18]=1[O:19][CH3:20])[CH:14]=O>>[CH3:9][O:10][C:11]1[CH:12]=[C:13](/[CH:14]=[C:6](/[C:3]2[CH:4]=[CH:5][S:1][CH:2]=2)\[C:7]#[N:8])[CH:16]=[CH:17][C:18]=1[O:19][CH3:20]

Participants

3

Reactant 2

HCID 8419VeratraldehydeHCID 837303-Thienylacetonitrile

Product 1

HCID 67228529HCID 67228529, compoundYield 65.3%

Procedure

3-Thiopheneacetonitrile (246 mg) was condensed with 3,4-dimethoxybenzaldehyde (332 mg) through Method B (production step 2), to thereby yield the target product (yield: 354 mg, 65%).

Sources & evidence

ORD record
ord-35ba3087f618464ba3642f95ed6522ac
Source dataset
uspto-grants-2014_04
Patent number
US08697742B2

Reaction notes

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