Veratraldehyde → HCID 5287171, compound

HRID 2366419Notes

Reaction equation

HRID 2366419 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][C:10]=1[O:11][CH3:12])[CH:6]=O.[S:13]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[N:15]=[C:14]1[CH2:22][C:23]#[N:24]>>[S:13]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[N:15]=[C:14]1/[C:22](=[CH:6]/[C:5]1[CH:8]=[CH:9][C:10]([O:11][CH3:12])=[C:3]([O:2][CH3:1])[CH:4]=1)/[C:23]#[N:24]

Participants

3

Reactant 2

HCID 8419VeratraldehydeHCID 3424652-(1,3-Benzothiazol-2-yl)acetonitrile

Product 1

HCID 5287171HCID 5287171, compoundYield 89.2%

Procedure

3,4-Dimethoxybenzaldehyde (191 mg) was condensed with 2-benzothiazoleacetonitrile (200 mg) through Method B (production step 2), to thereby yield the target product (yield: 330 mg, 89%).

Sources & evidence

ORD record
ord-52ae1f741819425f9cbdeee22184e437
Source dataset
uspto-grants-2014_04
Patent number
US08697742B2

Reaction notes

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