1-Benzothiophene-3-carbaldehyde → HCID 11964710, compound

HRID 2366435Notes

Reaction equation

HRID 2366435 reaction equation
[S:1]1[CH:5]=[C:4]([CH:6]=O)[C:3]2[CH:8]=[CH:9][CH:10]=[CH:11][C:2]1=2.[S:12]1[C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=2[N:14]=[C:13]1[CH2:21][C:22]#[N:23]>>[S:1]1[CH:5]=[C:4](/[CH:6]=[C:21](/[C:13]2[S:12][C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=3[N:14]=2)\[C:22]#[N:23])[C:3]2[CH:8]=[CH:9][CH:10]=[CH:11][C:2]1=2

Participants

3

Reactant 2

HCID 2273281-Benzothiophene-3-carbaldehydeHCID 3424652-(1,3-Benzothiazol-2-yl)acetonitrile

Product 1

HCID 11964710HCID 11964710, compoundYield 69.8%

Procedure

Benzo[b]thiophene-3-carboxaldehyde (81 mg) was condensed with 2-benzothiazoleacetonitrile (87 mg) through Method B (production step 3), to thereby yield the target product (yield: 111 mg, 69%).

Sources & evidence

ORD record
ord-f4d955aec5084f05a9930b661049aaf4
Source dataset
uspto-grants-2014_04
Patent number
US08697742B2

Reaction notes

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