3,4-Dimethoxybenzeneacetonitrile → HCID 11964713, compound

HRID 2366437Notes

Reaction equation

HRID 2366437 reaction equation
[Cl:1][C:2]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([CH:16]=O)=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[CH:7]2.[CH3:18][O:19][C:20]1[CH:21]=[C:22]([CH:26]=[CH:27][C:28]=1[O:29][CH3:30])[CH2:23][C:24]#[N:25]>>[Cl:1][C:2]1[C:3]2[C:8](=[CH:7][CH:6]=[CH:5][CH:4]=2)[C:9](/[CH:16]=[C:23](/[C:22]2[CH:26]=[CH:27][C:28]([O:29][CH3:30])=[C:20]([O:19][CH3:18])[CH:21]=2)\[C:24]#[N:25])=[C:10]2[C:15]=1[CH:14]=[CH:13][CH:12]=[CH:11]2

Participants

3

Reactant 2

HCID 667273,4-DimethoxybenzeneacetonitrileHCID 8270310-Chloro-9-anthraldehyde

Product 1

HCID 11964713HCID 11964713, compoundYield 56.1%

Procedure

10-Chloro-9-anthraldehyde (500 mg) was condensed with 3,4-dimethoxybenzyl cyanide (368 mg) through Method A (production step 2), to thereby yield the target product (yield: 466 mg, 56%).

Sources & evidence

ORD record
ord-531b4e508c034f688a8f534abab1e7f1
Source dataset
uspto-grants-2014_04
Patent number
US08697742B2

Reaction notes

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