2-Naphthalenecarboxaldehyde → HCID 5996728, compound

HRID 2366438Notes

Reaction equation

HRID 2366438 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH:11]=O.[CH3:13][O:14][C:15]1[CH:16]=[C:17]([CH:21]=[CH:22][C:23]=1[O:24][CH3:25])[CH2:18][C:19]#[N:20]>>[CH3:13][O:14][C:15]1[CH:16]=[C:17](/[C:18](=[CH:11]/[C:2]2[CH:3]=[CH:4][C:5]3[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=3)[CH:1]=2)/[C:19]#[N:20])[CH:21]=[CH:22][C:23]=1[O:24][CH3:25]

Participants

3

Reactant 2

HCID 62012-NaphthalenecarboxaldehydeHCID 667273,4-Dimethoxybenzeneacetonitrile

Product 1

HCID 5996728HCID 5996728, compoundYield 86.4%

Procedure

2-Naphthaldehyde (500 mg) was condensed with 3,4-dimethoxybenzyl cyanide (567 mg) through Method A (production step 2), to thereby yield the target product (yield: 872 mg, 86%).

Sources & evidence

ORD record
ord-791a4615fdf74bc48f308b03120713ed
Source dataset
uspto-grants-2014_04
Patent number
US08697742B2

Reaction notes

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