P-Toluenesulfonylhydrazide → HCID 178427625, compound

HRID 2366495Notes

Reaction equation

HRID 2366495 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:11][NH2:12])(=[O:10])=[O:9])=[CH:4][CH:3]=1.CN([CH:16]=[C:17]1[C:22](=[O:23])[CH2:21][CH2:20][CH2:19][C:18]1=[O:24])C>CCO>[O:23]=[C:22]1[CH2:21][CH2:20][CH2:19][C:18](=[O:24])[C:17]1=[CH:16][NH:12][NH:11][S:8]([C:5]1[CH:6]=[CH:7][C:2]([CH3:1])=[CH:3][CH:4]=1)(=[O:10])=[O:9]

Participants

4

Reactant 2

HCID 15303P-ToluenesulfonylhydrazideHCID 3593532-[(Dimethylamino)methylidene]cyclohexane-1,3-dione

Product 1

HCID 178427625HCID 178427625, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

According to Scheme 3 Step 1: 4-Methylbenzenesulfonohydrazide (44.6 mmol, 8.31 g) was added to a solution of 2-((dimethylamino)methylene)cyclohexane-1,3-dione (44.6 mmol, 7.46 g) in EtOH (50 mL) and the reaction mixture was stirred at room temperature for 5 minutes. After evaporation, 13.8 g (44.6 mmol, 100%) of N′-((2,6-dioxocyclohexylidene)methyl)-4-methylbenzenesulfonohydrazide were obtained as an orange oil.

Workup

  1. customAfter evaporation

Sources & evidence

ORD record
ord-ce0c360e71c14c04b674cf862caf49ed
Source dataset
uspto-grants-2014_04
Patent number
US08697744B2

Reaction notes

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