HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Bromo-2-methylquinoline → 2-Methylquinoline-8-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Bromo-2-methylquinoline | HCID 4715030 | — |
| Reactant | HCID 178418546 | HCID 178418546 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | 2-Methylquinoline-8-carbonitrile | HCID 33698227 | — |
Reaction Steps
Prepared by reacting 2-methyl-8-bromo-quinoline with copper(I)cyanide in N-methylpyrrolidinone under a protective gas atmosphere at 180° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08697868B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-80f7ee29a7bb4ea186e30718c222d38e |
| Source note | uspto-grants-2014_04 |