1-Phenethylamine, (-)- → HCID 67428375, compound

HRID 2366560Notes

Reaction equation

HRID 2366560 reaction equation
[F:1][C:2]1[CH:3]=[C:4]2[C:12](=[CH:13][CH:14]=1)[NH:11][C:10]1[CH2:9][CH2:8][C@H:7]([NH:15][C@@H:16]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[CH3:17])[CH2:6][C:5]2=1.C[C@H](N)C1C=CC=CC=1>>[F:1][C:2]1[CH:3]=[C:4]2[C:12](=[CH:13][CH:14]=1)[NH:11][C:10]1[CH2:9][CH2:8][C@@H:7]([NH:15][C@H:16]([C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=3)[CH3:17])[CH2:6][C:5]2=1

Participants

3

Reactant 2

HCID 758181-Phenethylamine, (-)-HCID 67427914HCID 67427914, compound

Product 1

HCID 67428375HCID 67428375, compound

Procedure

By following the same procedure as (S)-6-fluoro-N—((R)-1-phenylethyl)-2,3,4,9-tetrahydro-1H-carbazol-3-amine but using (S)-α-methylbenzylamine for the reductive amination, the title compound was obtained as a white solid.

Sources & evidence

ORD record
ord-8df4d15f1a204510ac4b82ef841b83e1
Source dataset
uspto-grants-2014_04
Patent number
US08697869B2

Reaction notes

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