HCID 66812215, compound → HCID 66812220, compound

HRID 2366562Notes

Reaction equation

HRID 2366562 reaction equation
[F:1][C:2]1[CH:3]=[C:4]2[C:12](=[CH:13][CH:14]=1)[NH:11][C:10]1[CH2:9][CH2:8][C@H:7]([NH2:15])[CH2:6][C:5]2=1.FC1C=C2C(=CC=1)NC1CC[C@@H](N[C@H](C3C=CC=CC=3)C)CC2=1>>[F:1][C:2]1[CH:3]=[C:4]2[C:12](=[CH:13][CH:14]=1)[NH:11][C:10]1[CH2:9][CH2:8][C@@H:7]([NH2:15])[CH2:6][C:5]2=1

Participants

3

Reactant 2

HCID 66812215HCID 66812215, compoundHCID 67428375HCID 67428375, compound

Product 1

HCID 66812220HCID 66812220, compound

Procedure

Following the same procedure as (S)-6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-amine, hydrogenation of (R)-6-fluoro-N—((S)-1-phenylethyl)-2,3,4,9-tetrahydro-1H-carbazol-3-amine (8.7 g, 0.028 mol) gave the title compound as a white solid.

Sources & evidence

ORD record
ord-b6cc1c662ceb4fba9ec8872d830c1d15
Source dataset
uspto-grants-2014_04
Patent number
US08697869B2

Reaction notes

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