Chloroform → HCID 53642313, compound

HRID 236659Notes

Reaction equation

[CH3:1][C@:2]1([CH2:16][CH2:17]O)[CH2:11][CH2:10][C:9]2[C:4](=[C:5]([CH3:15])[C:6]([CH3:14])=[C:7]([OH:13])[C:8]=2[CH3:12])[O:3]1.C(Cl)(Cl)[Cl:20]>>[CH3:1][C@:2]1([CH2:16][CH2:17][Cl:20])[CH2:11][CH2:10][C:9]2[C:4](=[C:5]([CH3:15])[C:6]([CH3:14])=[C:7]([OH:13])[C:8]=2[CH3:12])[O:3]1

Participants

Reactant 2

HCID 6212Chloroform

HCID 10332355HCID 10332355, compound

Product 1

HCID 53642313HCID 53642313, compound

Procedure

(R)-2,5,7,8-tetramethyl-6-hydroxy-2-(2-chloroethyl)-chroman was prepared from (R)-2,5,7,8-tetramethyl-6-hydroxy-2-(2-hydroxyethyl)-chroman by a procedure similar to that described in Example 10. [α]D20 =+9.0, (c=2, chloroform), mp.=111° C.

Sources & evidence

ORD record: ord-f8e47bfb32214becbdabc611d9425803
Source dataset: uspto-grants-1987_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04645845

Reaction notes

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