Oxalyl chloride → HCID 57447102, compound

Participants

Reaction Steps

The method described in Part D of Example 53 was used to treat 6-[2-(ethoxymethyl)-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl]hexanoic acid (3.23 g, 9.4 mmol) with oxalyl chloride (3.29 mL, 37.7 mmol) to obtain 6-[2-(ethoxymethyl)-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl]hexanoyl chloride. The reaction was complete in two hours.

Provenance & Evidence