Dichloromethane → HCID 86762342, compound

Participants

Reaction Steps

1,1-Dimethylethyl 4-(2-{4-[(cis)-1-acetyl-2-methyl-4-({[(1-methylethyl)oxy]carbonyl}amino)-1,2,3,4-tetrahydro-6-quinolinyl]-1H-pyrazol-1-yl}ethyl)-1-piperazinecarboxylate (for a preparation see Intermediate 38) (65 mg, 0.114 mmol) was dissolved in dichloromethane (DCM) (1 mL), mixed with trifluoroacetic acid (0.5 mL, 6.49 mmol) and stirred under nitrogen. The product was concentrated, dissolved in MeOH (1.5 mL), mixed with 1.25M HCl (157 μL) and blown down to dryness to give a white solid (41 mg).

Provenance & Evidence