HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 70604051, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 8-Chloro-6-phenyl-4H-pyrazolo[1,5-a][1,4]benzodiazepine-2-carboxylic acid, methyl ester | HCID 12377884 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 70604051 | HCID 70604051 | — |
Reaction Steps
A mixture of 1.05 g. (3 mmol) of the end product of Example 9 in 3 ml. acetone and 30 ml. of 1 N HCl was heated to reflux for 2 hours. After cooling to room temperature, the mixture was concentrated in vacuo and the residue recrystallized twice from H2O/acetone/ether to give analytically pure end product as off-white prisms: mp 268°-269°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04157331 |
| Source dataset | uspto-grants-1979_06 |
| ORD ID | ord-2e1d8218f32c4db4b09be4812730c4ed |
| Source note | uspto-grants-1979_06 |