2-Amino-4,6-dichloropyrimidine → HCID 178508445, compound

Participants

Reaction Steps

A solution of 2-[4-(3-chlorophenyl)-1H-imidazol-2-yl]morpholine (600 mg, 2.0 mmol), 4,6-dichloro-2-pyrimidinamine (328 mg, 2.0 mmol) and Hunig's base (0.870 mL, 5.00 mmol) in ethanol (80 mL) was heated overnight at 85° C. The reaction mixture was filtered and concentrated to afford the crude title compound (1.1 g) as a brown oil. LC-MS (ES) m/z=391 [M+H]+.

Provenance & Evidence