HCID 11344952, compound → 1,3-Dioxooctahydroisobenzofuran-5-carboxylic acid

HRID 2367850Notes

Reaction equation

[CH:1]1([C:13]([OH:15])=[O:14])[CH2:6][CH2:5][CH:4]([C:7]([OH:9])=[O:8])[CH2:3][CH:2]1[C:10]([OH:12])=O>O>[CH:1]12[C:13](=[O:14])[O:15][C:10](=[O:12])[CH:2]1[CH2:3][CH:4]([C:7]([OH:9])=[O:8])[CH2:5][CH2:6]2

Participants

Conditions

Temperature: 250 °C

Procedure

Into a four-necked flask equipped with a thermometer, a stirrer, a condenser and a temperature controller, 100 parts by mass of cyclohexane-1,2,4-tricarboxylic acid was placed and melted by heating at 250° C. for 3 hours while formed water was removed to the outside of the system with a stream of nitrogen gas, and 1,2,4-cyclohexanetricarboxylic acid 1,2-anhydride was obtained. as a light yellow transparent liquid substance The yield of the anhydride was 95% based on the amount of cyclohexane-1,2,4-tricarboxylic acid used as the raw material. The obtained liquid 1,2,4-cyclohexanetricarboxylic acid had a viscosity of 14.6 Pa·s at 60° C.

Workup

customInto a four-necked flask equipped with a thermometer, a stirrer, a condenser
customwas removed to the outside of the system with a stream of nitrogen gas

Sources & evidence

ORD record: ord-15eaae2f7f1d4c6284b5b6ee287e7b5c
Source dataset: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08703010B2

Reaction notes

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