HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromopropane → tert-butyl [(1S)-1-methyl-2-{[1-(5-propoxy-1,3-benzoxazol-2-yl)piperidin-4-yl]oxy}ethyl]carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromopropane | HCID 7840 | — |
| Reactant | tert-butyl [(1S)-2-{[1-(5-hydroxy-1,3-benzoxazol-2-yl)piperidin-4-yl]oxy}-1-methylethyl]carbamate | HCID 86658695 | — |
| Product | tert-butyl [(1S)-1-methyl-2-{[1-(5-propoxy-1,3-benzoxazol-2-yl)piperidin-4-yl]oxy}ethyl]carbamate | HCID 86658698 | — |
Reaction Steps
By a method similar to Example 6, step A, and using tert-butyl [(1S)-2-{[1-(5-hydroxy-1,3-benzoxazol-2-yl)piperidin-4-yl]oxy}-1-methylethyl]carbamate (412 mg) and 1-bromopropane (0.282 mL), the title compound (367 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08703758B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-3eb5b85f71d54d8fad0e1b732821033a |
| Source note | uspto-grants-2014_04 |