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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2368255Generated: October 30, 2026

2,5-Dimethylpyrrolidine → HCID 58548330, compound

https://huagongshe.com/reaction/2368255

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-DimethylpyrrolidineHCID 96034—
Reactant4-{[6-Cyclopropyl-3-(pyrimidin-5-ylamino)-pyridine-2-carbonyl]-amino}-1-methyl-1H-pyrazole-3-carboxylic acid methyl esterHCID 70099200—
ProductHCID 58548330HCID 5854833010%

Reaction Steps

According to the general method described in step 5 of example 27, reaction of 2,5-dimethylpyrrolidine with 4-{[6-cyclopropyl-3-(pyrimidin-5-ylamino)-pyridine-2-carbonyl]-amino}-1-methyl-1H-pyrazole-3-carboxylic acid methyl ester provided the title compound (10%) as amorphous yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08703768B2
Source datasetuspto-grants-2014_04
ORD IDord-b9f86f1b289d4ee49981aac4569127d3
Source noteuspto-grants-2014_04