HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → 2-Amino-6-methoxy-N,N-dimethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 2-Amino-6-methoxybenzoic Acid | HCID 2735357 | — |
| Product | 2-Amino-6-methoxy-N,N-dimethyl-benzamide | HCID 70096784 | — |
Reaction Steps
The product was obtained starting from 2-amino-6-methoxybenzoic acid (100 mg, 0.6 mmol) and dimethylamine (2M in THF, 420 μl, 0.84 mmol) according to the method described in example 64, step 6 after extraction with ethyl acetate and purification by silica gel chromatography using an amine phase and a heptane/ethyl acetate gradient as colorless oil (26 mg, 22%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08703768B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-6e10eeb8b0a949db9142fe348ce457b6 |
| Source note | uspto-grants-2014_04 |