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HRID2368368

反应详情

EQUATION

反应方程式

HRID 2368368 的结构方程式

REACTANTS

反应物

2
结构：CN1CCCC(N)C1.Cl.Cl
HCID17750342

1-Methylpiperidin-3-amine--hydrogen chloride (1/2)

C6H16Cl2N2

结构：Cn1ncc(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)c1C(=O)O
HCID70098073

未命名化合物

PRODUCTS

生成物

1
结构：CN1CCCC(NC(=O)c2c(NC(=O)c3nc(C4CC4)cnc3Nc3cncnc3)cnn2C)C1
HCID54762014

未命名化合物

PROCEDURE

实验过程

The product was obtained starting from 4-{[6-cyclopropyl-3-(pyrimidin-5-ylamino)-pyrazine-2-carbonyl]-amino}-2-methyl-2H-pyrazole-3-carboxylic acid (25 mg, 66 μmol; example 236, step 3) and 1-methyl-piperidin-3-ylamine dihydrochloride (12 mg, 66 μmol) according to the method described in example 64, step 6 after purification by preparative HPLC using an acetonitrile/water gradient as yellow solid (11 mg, 33%).

WORKUP

后处理

  1. customThe product was obtained
  2. customafter purification by preparative HPLC