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HRID2368382

反应详情

EQUATION

反应方程式

HRID 2368382 的结构方程式

REACTANTS

反应物

2
结构：CN1CC(N)C1.Cl.Cl
HCID44784901

1-Methylazetidin-3-amine--hydrogen chloride (1/2)

C4H12Cl2N2

结构：Cn1ncc(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)c1C(=O)O
HCID70098073

未命名化合物

PRODUCTS

生成物

1
结构：CN1CC(NC(=O)c2c(NC(=O)c3nc(C4CC4)cnc3Nc3cncnc3)cnn2C)C1
HCID54760944

未命名化合物

PROCEDURE

实验过程

The product was obtained starting from 4-{[6-cyclopropyl-3-(pyrimidin-5-ylamino)-pyrazine-2-carbonyl]-amino}-2-methyl-2H-pyrazole-3-carboxylic acid (30 mg, 79 μmol; example 236, step 3) and 1-methylazetidin-3-amine dihydrochloride (16 mg, 100 μmol) according to the method described in example 64, step 6 after purification by preparative HPLC using an acetonitrile/water gradient as yellow solid (11 mg, 31%).

WORKUP

后处理

  1. customThe product was obtained
  2. customafter purification by preparative HPLC