HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Tolyl isocyanate → HCID 57513608, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Tolyl isocyanate | HCID 69194 | — |
| Reactant | HCID 57513606 | HCID 57513606 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 57513608 | HCID 57513608 | — |
Reaction Steps
2-Amino-N-(benzyl-4-phenyl-thiazol-2-yl)-2-methyl-propionamide (100 mg, 0.3 mmol) and o-tolyl isocyanate (36 mg, 0.3 mmol) were stirred as a solution in DCM (5 mL). Purification via HPLC afforded the title compound. 1H NMR (400 MHz, CHLOROFORM-D) δ 1.58 (s, 6H) 2.22 (s, 3H) 4.13 (s, 2H) 5.76 (s, 1H) 7.15, (s, 5H) 7.32 (s, 4H) 7.50 (s, 6H). m/z 485.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08703761B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-7139795328c84ff18545d67d0da81cf0 |
| Source note | uspto-grants-2014_04 |