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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2368400Generated: November 1, 2026

2-Tolyl isocyanate → HCID 57513608, compound

https://huagongshe.com/reaction/2368400

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Tolyl isocyanateHCID 69194—
ReactantHCID 57513606HCID 57513606—
SolventDichloromethaneHCID 6344—
ProductHCID 57513608HCID 57513608—

Reaction Steps

2-Amino-N-(benzyl-4-phenyl-thiazol-2-yl)-2-methyl-propionamide (100 mg, 0.3 mmol) and o-tolyl isocyanate (36 mg, 0.3 mmol) were stirred as a solution in DCM (5 mL). Purification via HPLC afforded the title compound. 1H NMR (400 MHz, CHLOROFORM-D) δ 1.58 (s, 6H) 2.22 (s, 3H) 4.13 (s, 2H) 5.76 (s, 1H) 7.15, (s, 5H) 7.32 (s, 4H) 7.50 (s, 6H). m/z 485.2 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08703761B2
Source datasetuspto-grants-2014_04
ORD IDord-7139795328c84ff18545d67d0da81cf0
Source noteuspto-grants-2014_04